Collagen VII (COL7A1) (NM_000094) Human Recombinant Protein

CAT#: TP318470

Purified recombinant protein of Human collagen, type VII, alpha 1 (COL7A1), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Product Images

Purified recombinant protein COL7A1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC218470, encoding the full-length of COL7A1
• Tag: Myc-DDK
• Predicted MW: 295.22 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl, 100 mM glycine, 10% glycerol, pH7.3
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000085
• Locus ID: 1294
• UniProt ID: Q02388, Q59F16
• Cytogenetics: 3p21.31
• Refseq Size: 9272
• Refseq ORF: 8832
• Synonyms: EBD1; EBDCT; EBR1; NDNC8
• Summary: 'This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome