Uroguanylin (GUCA2B) (NM_007102) Human Recombinant Protein

CAT#: TP321085

Recombinant protein of human guanylate cyclase activator 2B (uroguanylin) (GUCA2B)

Product Images

Coomassie blue staining of purified GUCA2B protein (Cat# TP321085). The protein was produced from HEK293T cells transfected with GUCA2B cDNA clone (Cat# RC221085) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC221085. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 11.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_009033
• Locus ID: 2981
• UniProt ID: Q16661
• Cytogenetics: 1p34.2
• Refseq Size: 597
• Refseq ORF: 336
• Synonyms: GCAP-II; UGN
• Summary: 'This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]'
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane