IL1 Receptor II (IL1R2) (NM_004633) Human Recombinant Protein
CAT#: TP321860
Recombinant protein of human interleukin 1 receptor, type II (IL1R2), transcript variant 1
View other "IL1R2" proteins (7)
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC221860. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 43.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_004624 |
Locus ID | 7850 |
UniProt ID | P27930 |
Cytogenetics | 2q11.2 |
Refseq Size | 1484 |
Refseq ORF | 1194 |
Synonyms | CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB |
Summary | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401469 | IL1R2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
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LC406630 | IL1R2 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401469 | Transient overexpression lysate of interleukin 1 receptor, type II (IL1R2), transcript variant 1 |
USD 396.00 |
|
LY406630 | Transient overexpression lysate of interleukin 1 receptor, type II (IL1R2), transcript variant 2 |
USD 396.00 |
|
PH307914 | IL1R2 MS Standard C13 and N15-labeled recombinant protein (NP_775465) |
USD 2,055.00 |
|
PH321860 | IL1R2 MS Standard C13 and N15-labeled recombinant protein (NP_004624) |
USD 2,055.00 |
|
TP307914 | Recombinant protein of human interleukin 1 receptor, type II (IL1R2), transcript variant 2 |
USD 439.00 |
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