IL6R (NM_000565) Human Recombinant Protein
CAT#: TP321874
Recombinant protein of human interleukin 6 receptor (IL6R), transcript variant 1
View other "IL6R" proteins (7)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC221874. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 49.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000556 |
Locus ID | 3570 |
UniProt ID | P08887, A0N0L5 |
Cytogenetics | 1q21.3 |
Refseq Size | 4176 |
Refseq ORF | 1404 |
Synonyms | CD126; gp80; HIES5; IL-6R-1; IL-6RA; IL6Q; IL6QTL; IL6RA; IL6RQ |
Summary | 'This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]' |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400192 | IL6R HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC405751 | IL6R HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400192 | Transient overexpression lysate of interleukin 6 receptor (IL6R), transcript variant 1 |
USD 605.00 |
|
LY405751 | Transient overexpression lysate of interleukin 6 receptor (IL6R), transcript variant 2 |
USD 396.00 |
|
PH319601 | IL6R MS Standard C13 and N15-labeled recombinant protein (NP_852004) |
USD 2,055.00 |
|
PH321874 | IL6R MS Standard C13 and N15-labeled recombinant protein (NP_000556) |
USD 2,055.00 |
|
TP319601 | Recombinant protein of human interleukin 6 receptor (IL6R), transcript variant 2 |
USD 788.00 |
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