JNK1 (MAPK8) (NM_139046) Human Recombinant Protein
CAT#: TP322829
Purified recombinant protein of Homo sapiens mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-b1
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC222829. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 43.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_620634 |
Locus ID | 5599 |
UniProt ID | P45983 |
Cytogenetics | 10q11.22 |
Refseq Size | 1417 |
Refseq ORF | 1152 |
Synonyms | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c |
Summary | 'The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]' |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase |
Protein Pathways | Adipocytokine signaling pathway, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, GnRH signaling pathway, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, Wnt signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400970 | MAPK8 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC408400 | MAPK8 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC408401 | MAPK8 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC408403 | MAPK8 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC430088 | MAPK8 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400970 | Transient overexpression lysate of mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a1 |
USD 396.00 |
|
LY408400 | Transient overexpression lysate of mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-b1 |
USD 396.00 |
|
LY408401 | Transient overexpression lysate of mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-b2 |
USD 605.00 |
|
LY408403 | Transient overexpression lysate of mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a2 |
USD 605.00 |
|
LY430088 | Transient overexpression lysate of mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-b1 |
USD 396.00 |
|
PH318407 | MAPK8 MS Standard C13 and N15-labeled recombinant protein (NP_002741) |
USD 2,055.00 |
|
PH322829 | MAPK8 MS Standard C13 and N15-labeled recombinant protein (NP_620634) |
USD 2,055.00 |
|
PH322874 | MAPK8 MS Standard C13 and N15-labeled recombinant protein (NP_620635) |
USD 2,055.00 |
|
PH322925 | MAPK8 MS Standard C13 and N15-labeled recombinant protein (NP_620637) |
USD 2,055.00 |
|
TP318407 | Recombinant protein of human mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a1 |
USD 788.00 |
|
TP322874 | Recombinant protein of human mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-b2 |
USD 748.00 |
|
TP322925 | Recombinant protein of human mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a2 |
USD 748.00 |
{0} Product Review(s)
Be the first one to submit a review