WNK4 (NM_032387) Human Recombinant Protein

CAT#: TP323269

Recombinant protein of human WNK lysine deficient protein kinase 4 (WNK4)

Product Images

Coomassie blue staining of purified WNK4 protein (Cat# TP323269). The protein was produced from HEK293T cells transfected with WNK4 cDNA clone (Cat# RC223269) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC223269. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 134.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_115763
• Locus ID: 65266
• UniProt ID: Q96J92
• Cytogenetics: 17q21.2
• Refseq Size: 4147
• Refseq ORF: 3729
• Synonyms: PHA2B; PRKWNK4
• Summary: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB. [provided by RefSeq, Sep 2009]
• Protein Families: Druggable Genome, Protein Kinase