XPF (ERCC4) (NM_005236) Human Recombinant Protein

CAT#: TP323300

Recombinant protein of human excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4)

Product Images

Coomassie blue staining of purified ERCC4 protein (Cat# TP323300). The protein was produced from HEK293T cells transfected with ERCC4 cDNA clone (Cat# RC223300) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC223300. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 104.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_005227
• Locus ID: 2072
• UniProt ID: Q92889, A0A1W1GSK9
• Cytogenetics: 16p13.12
• Refseq Size: 2751
• Refseq ORF: 2748
• Synonyms: ERCC11; FANCQ; RAD1; XFEPS; XPF
• Summary: 'The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]'
• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair