Caldesmon (CALD1) (NM_033157) Human Recombinant Protein

CAT#: TP323989

Recombinant protein of human caldesmon 1 (CALD1), transcript variant 3

Product Images

Coomassie blue staining of purified CALD1 protein (Cat# TP323989). The protein was produced from HEK293T cells transfected with CALD1 cDNA clone (Cat# RC223989) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC223989. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 65.4 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_149347
• Locus ID: 800
• UniProt ID: Q05682
• Cytogenetics: 7q33
• Refseq Size: 4546
• Refseq ORF: 1692
• Synonyms: CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22
• Summary: 'This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]'
• Protein Pathways: Vascular smooth muscle contraction