NTE (PNPLA6) (NM_001166111) Human Recombinant Protein

CAT#: TP328678

Recombinant protein of human patatin-like phospholipase domain containing 6 (PNPLA6), transcript variant 1.

Product Images

Coomassie blue staining of purified PNPLA6 protein (Cat# TP328678). The protein was produced from HEK293T cells transfected with PNPLA6 cDNA clone (Cat# RC228678) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC228678. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 150.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: NULL or Add: Recombinant proteins was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001159583
• Locus ID: 10908
• UniProt ID: Q8IY17
• Cytogenetics: 19p13.2
• Refseq ORF: 4125
• Synonyms: BNHS; iPLA2delta; LNMS; NTE; NTEMND; OMCS; SPG39; sws
• Summary: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
• Protein Families: Transmembrane