MAN1 (LEMD3) (NM_001167614) Human Recombinant Protein

CAT#: TP330581

Recombinant protein of human LEM domain containing 3 (LEMD3), transcript variant 2.

Product Images

Coomassie blue staining of purified LEMD3 protein (Cat# TP330581). The protein was produced from HEK293T cells transfected with LEMD3 cDNA clone (Cat# RC230581) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC230581. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 100.3
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: NULL or Add: Recombinant proteins was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001161086
• Locus ID: 23592
• UniProt ID: Q9Y2U8
• Cytogenetics: 12q14.3
• Refseq ORF: 2730
• Synonyms: MAN1
• Summary: This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis. [provided by RefSeq, Nov 2009]
• Protein Families: Transmembrane