Gck (BC011139) Mouse Recombinant Protein

CAT#: TP507435

Purified recombinant protein of Mouse glucokinase (cDNA clone MGC:18414 IMAGE:4195943), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Tag: C-MYC/DDK
• Predicted MW: 51.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Reference Data

• Locus ID: 103988
• Cytogenetics: 11 3.88 cM
• Refseq Size: 1798
• Refseq ORF: 1395
• Synonyms: GLK, Gk, HK4, HKIV, HXKP, MODY2, NIDDM
• Summary: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. [UniProtKB/Swiss-Prot Function]