Cyp17a1 (NM_007809) Mouse Recombinant Protein

CAT#: TP508156

Purified recombinant protein of Mouse cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR208156, encoding Mouse full-length Cyp17a1.
• Tag: C-MYC/DDK
• Predicted MW: 57.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_031835
• Locus ID: 13074
• UniProt ID: P27786, Q53YJ1, Q3UYU1
• Cytogenetics: 19 38.97 cM
• Refseq Size: 1841
• Refseq ORF: 1524
• Synonyms: Cyp17; p450c17
• Summary: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. [UniProtKB/Swiss-Prot Function]