Cyp17a1 (NM_007809) Mouse Recombinant Protein
CAT#: TP508156
Purified recombinant protein of Mouse cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
A DNA sequence from Mouse cDNA ORF Clone, MR208156, encoding Mouse full-length Cyp17a1.
|
Tag | C-MYC/DDK |
Predicted MW | 57.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_031835 |
Locus ID | 13074 |
UniProt ID | P27786, Q53YJ1, Q3UYU1 |
Cytogenetics | 19 38.97 cM |
Refseq Size | 1841 |
Refseq ORF | 1524 |
Synonyms | Cyp17; p450c17 |
Summary | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. [UniProtKB/Swiss-Prot Function] |
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