Ptpre (NM_011212) Mouse Recombinant Protein

CAT#: TP521802

Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, E (Ptpre), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR221802, encoding Mouse full-length Ptpre.
• Tag: C-MYC/DDK
• Predicted MW: 81.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_035342
• Locus ID: 19267
• UniProt ID: P49446
• Cytogenetics: 7 81.27 cM
• Refseq Size: 5411
• Refseq ORF: 2097
• Synonyms: PTPe; PTPepsilon; RPTPepsilon
• Summary: Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+). [UniProtKB/Swiss-Prot Function]