Kcnj5 (NM_010605) Mouse Recombinant Protein

CAT#: TP526110

Purified recombinant protein of Mouse potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from Mouse cDNA ORF Clone, MR226110, encoding Mouse full-length Kcnj5.
• Tag: C-MYC/DDK
• Predicted MW: 48.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_034735
• Locus ID: 16521
• UniProt ID: P48545
• Cytogenetics: 9 17.65 cM
• Refseq Size: 4496
• Refseq ORF: 1257
• Synonyms: CIR; GIRK4; KATP-1; Kir3.4
• Summary: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. [UniProtKB/Swiss-Prot Function]