Stanniocalcin 1 (STC1) (NM_003155) Human Recombinant Protein

CAT#: TP700021

Recombinant protein of mature form of human stanniocalcin 1 (STC1) with C-terminal DDK/His tag, expressed in human cells


  View other "STC1" proteins (3)

USD 748.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC206573, encoding the mature form (Thr34-Ala247) of human STC1
Tag C-DDK/His
Predicted MW 26 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003146
Locus ID 6781
UniProt ID P52823
Cytogenetics 8p21.2
Refseq Size 3897
Refseq ORF 741
Synonyms STC
Summary 'This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, Secreted Protein

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