RON (MST1R) (NM_002447) Human Recombinant Protein

CAT#: TP700132

Purified recombinant protein of human macrophage stimulating 1 receptor (c-met-related tyrosine kinase)(MST1R), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC600032, encoding the region (Glu25-Thr957) of human MST1R
• Tag: C-DDK/His
• Predicted MW: 102 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002438
• Locus ID: 4486
• UniProt ID: Q04912
• Cytogenetics: 3p21.31
• Refseq Size: 4785
• Refseq ORF: 2871
• Synonyms: CD136; CDw136; NPCA3; PTK8; RON
• Summary: 'This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]'
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane