Eph receptor A2 (EPHA2) (NM_004431) Human Recombinant Protein

CAT#: TP700138

Purified recombinant protein of Human EPH receptor A2 (EPHA2), with C-terminal DDK/His tag, expressed in human cells

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC600038, encoding the extracellular domain (Ala24-Val537) of human EPHA2
• Tag: C-DDK/His
• Predicted MW: 59 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_004422
• Locus ID: 1969
• UniProt ID: P29317, A0A024QZA8
• Cytogenetics: 1p36.13
• Refseq Size: 3970
• Refseq ORF: 1611
• Synonyms: ARCC2; CTPA; CTPP1; CTRCT6; ECK
• Summary: 'This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]'
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance