Eph receptor A6 (EPHA6) (NM_001080448) Human Recombinant Protein

CAT#: TP700143

Purified recombinant protein of human EPH receptor A6 (EPHA6), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC600043, encoding the region (Ala23 – Ser549) of human EPHA6
• Tag: C-DDK/His
• Predicted MW: 62 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001073917
• Locus ID: 285220
• UniProt ID: A0A0B4J1T8, B3KS12
• Cytogenetics: 3q11.2
• Refseq Size: 3677
• Refseq ORF: 1647
• Synonyms: EHK-2; EHK2; EK12; EPA6; HEK12; PRO57066
• Summary: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. [UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance