EPHA8 (NM_020526) Human Recombinant Protein
CAT#: TP700145
Purified recombinant protein of human EPH receptor A8 (EPHA8), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells
Other products for "EPHA8"
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC600045, encoding the region (Ala28-Thr542) of human EPHA8
|
Tag | C-DDK/His |
Predicted MW | 60 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS, pH7.4, 10% glycerol |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_065387 |
Locus ID | 2046 |
UniProt ID | P29322 |
Cytogenetics | 1p36.12 |
Refseq Size | 4996 |
Refseq ORF | 1626 |
Synonyms | EEK; EK3; HEK3 |
Summary | 'This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | Axon guidance |
Documents
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