TIE2 (TEK) (NM_000459) Human Recombinant Protein

CAT#: TP700157

Purified recombinant protein of human TEK tyrosine kinase (TEK), endothelial, with C-terminal DDK/His tag, expressed in human cells, 20 µg


  View other "TEK" proteins (3)

USD 748.00

In Stock*

Size
    • 20 ug

Product Images

Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC600057, encoding the region (Ala23– Leu748) of human TEK
Tag C-DDK/His
Predicted MW 84 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000450
Locus ID 7010
UniProt ID Q02763, Q59HG2
Cytogenetics 9p21.2
Refseq Size 4787
Refseq ORF 2244
Synonyms CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1
Summary 'This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]'
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane

Documents

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.