TIM 3 (HAVCR2) (NM_032782) Human Recombinant Protein

CAT#: TP700234

Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal DDK/His tag, expressed in human cells, 20 µg


  View other "HAVCR2" proteins (5)

USD 748.00

In Stock*

Size
    • 20 ug

Product Images

Other products for "HAVCR2"

Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC209440, encoding the region (Glu23-Arg200) of human TIM3
Tag C-DDK/His
Predicted MW 23 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH7.4, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_116171
Locus ID 84868
UniProt ID Q8TDQ0
Cytogenetics 5q33.3
Refseq Size 2448
Refseq ORF 903
Synonyms CD366; HAVcr-2; KIM-3; SPTCL; Tim-3; TIM3; TIMD-3; TIMD3
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Protein Families Druggable Genome, Transmembrane

Documents

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.