Angiopoietin like 4 (ANGPTL4) (NM_139314) Human Recombinant Protein
CAT#: TP700268
Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 µg
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC205651, encoding the region (Gly26 – Arg161) of human ANGPTL4
|
Tag | C-DDK/His |
Predicted MW | 18 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | PBS, pH7.4, 10% glycerol |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_647475 |
Locus ID | 51129 |
UniProt ID | Q9BY76 |
Cytogenetics | 19p13.2 |
Refseq Size | 1905 |
Refseq ORF | 1218 |
Synonyms | ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171 |
Summary | This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | PPAR signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403389 | ANGPTL4 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC422106 | ANGPTL4 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403389 | Transient overexpression lysate of angiopoietin-like 4 (ANGPTL4), transcript variant 1 |
USD 396.00 |
|
LY422106 | Transient overexpression lysate of angiopoietin-like 4 (ANGPTL4), transcript variant 3 |
USD 396.00 |
|
TP700267 | Purified recombinant protein of human angiopoietin-like 4 (ANGPTL4), transcript variant 1, with N-terminal His/DDK tag, expressed in human cells, 20 µg |
USD 748.00 |
|
TP762023 | Purified recombinant protein of Human angiopoietin-like 4 (ANGPTL4), transcript variant 1,Gln53-Ser301, with N-terminal His tag, expressed in E. coli, 50ug |
USD 215.00 |
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