Thyroxine Binding Globulin (SERPINA7) (NM_000354) Human Recombinant Protein

CAT#: TP701058

Purified recombinant protein of Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 (SERPINA7), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug


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USD 748.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC204733, encoding the region Ala21-Ala415 of SERPINA7
Tag C-His
Predicted MW 45.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS,pH7.4,10% glycerol;
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000345
Locus ID 6906
UniProt ID P05543
Cytogenetics Xq22.3
Refseq Size 1600
Refseq ORF 1245
Synonyms TBG; TBGQTL
Summary 'There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012]'
Protein Families Druggable Genome, Secreted Protein

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