TREM2 (NM_018965) Human Recombinant Protein

CAT#: TP701236

Purified recombinant protein of Human triggering receptor expressed on myeloid cells 2 (TREM2), Met1-Ser174, with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Product Images

Purified recombinant protein TREM2 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC221132, encoding the region Met1-Ser174 of TREM2
• Tag: C-HIS
• Predicted MW: 18.28 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH7.4, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_061838
• Locus ID: 54209
• UniProt ID: Q9NZC2, Q5TCX1
• Cytogenetics: 6p21.1
• Refseq Size: 1041
• Refseq ORF: 690
• Synonyms: PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
• Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane