Desmin (DES) (NM_001927) Human Recombinant Protein

CAT#: TP710055

Recombinant protein of human desmin(DES),full length,with C-terminal flag tag, expressed in sf9 cells

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC205685, encoding human full-length DES
• Tag: C-DDK
• Predicted MW: 54 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris-HCl pH8.0, 150mM NaCl, 10%glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001662
• Locus ID: 1674
• UniProt ID: P17661, P07306, Q53SB5, Q6FGQ5
• Cytogenetics: 2q35
• Refseq Size: 1519
• Refseq ORF: 873
• Synonyms: CDCD3; CMD1F; CSM1; CSM2; LGMD1D; LGMD1E; LGMD2R
• Summary: 'This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)