MERTK (NM_006343) Human Recombinant Protein

CAT#: TP710107

Recombinant protein of human c-mer proto-oncogene tyrosine kinase (MERTK), residues 21-505aa, with C-terminal DDK tag, expressed in sf9, 20ug


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USD 425.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC215289, encoding the region(Met-Ala21-Ile505) of Homo sapiens MERTK
Tag C-DDK
Predicted MW 52.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_006334
Locus ID 10461
UniProt ID Q12866
Cytogenetics 2q13
Refseq Size 3632
Refseq ORF 2997
Synonyms c-Eyk; c-mer; MER; RP38; Tyro12
Summary This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Protein Kinase, Transmembrane

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