LYRIC (MTDH) (NM_178812) Human Recombinant Protein

CAT#: TP710116

Recombinant protein of human metadherin (MTDH), residues 70-582aa, with N-terminal His tag,expressed in sf9 cells


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USD 425.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC207238, encoding the region(Met-Gly70-Thr582) of Homo sapiens MTDH
Tag N-His
Predicted MW 56.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_848927
Locus ID 92140
UniProt ID Q86UE4, A0A024R9D2
Cytogenetics 8q22.1
Refseq Size 7667
Refseq ORF 1746
Synonyms 3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3
Summary Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance. [UniProtKB/Swiss-Prot Function]
Protein Families Transmembrane

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