Desmoglein 1 (DSG1) (NM_001942) Human Recombinant Protein
CAT#: TP710406
Purified recombinant protein of Human desmoglein 1 (DSG1), Gln47-Gly547, with C-DDK-Myc-His tag, expressed in sf9
Other products for "DSG1"
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC225054, encoding the Gln47-Gly547 of DSG1
|
Tag | C-DDK |
Predicted MW | 62.8 kDa |
Concentration | >50 ug/mL as determined by microplate Bradford method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001933 |
Locus ID | 1828 |
UniProt ID | Q02413 |
Cytogenetics | 18q12.1 |
Refseq Size | 5447 |
Refseq ORF | 3147 |
Synonyms | CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1 |
Summary | 'This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]' |
Protein Families | Druggable Genome |
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