Desmoglein 1 (DSG1) (NM_001942) Human Recombinant Protein

CAT#: TP710406

Purified recombinant protein of Human desmoglein 1 (DSG1), Gln47-Gly547, with C-DDK-Myc-His tag, expressed in sf9

Product Images

Purified recombinant protein DSG1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC225054, encoding the Gln47-Gly547 of DSG1
• Tag: C-DDK
• Predicted MW: 62.8 kDa
• Concentration: >50 ug/mL as determined by microplate Bradford method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001933
• Locus ID: 1828
• UniProt ID: Q02413
• Cytogenetics: 18q12.1
• Refseq Size: 5447
• Refseq ORF: 3147
• Synonyms: CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1
• Summary: 'This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]'
• Protein Families: Druggable Genome