CCL27 (NM_006664) Human Recombinant Protein
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Phe25-Gly112
|
Tag | tag free |
Predicted MW | 10.1 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 500mM NaCl, pH 7.5. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_006655 |
Locus ID | 10850 |
UniProt ID | Q9Y4X3, Q5VZ77 |
Cytogenetics | 9p13.3 |
Synonyms | ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 |
Summary | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014] |
Protein Families | Druggable Genome |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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