Protein phosphatase inhibitor 1 (PPP1R1A) (NM_006741) Human Recombinant Protein

CAT#: TP720141L

Recombinant protein of human protein phosphatase 1, regulatory (inhibitor) subunit 1A (PPP1R1A)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Val171
• Tag: C-His
• Predicted MW: 20 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.5.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_006732
• Locus ID: 5502
• UniProt ID: Q13522
• Cytogenetics: 12q13.2
• Synonyms: I1; IPP1
• Summary: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.[UniProtKB/Swiss-Prot Function]
• Protein Families: Druggable Genome
• Protein Pathways: Long-term potentiation