LAP2 (TMPO) (NM_001032283) Human Recombinant Protein

CAT#: TP720158XL

Recombinant protein of human thymopoietin (TMPO), transcript variant 2

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Pro2-Glu187
• Tag: C-His
• Predicted MW: 21.6 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at -80°C.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001027454
• Locus ID: 7112
• UniProt ID: P42167, A0A024RBE7, Q59G12
• Cytogenetics: 12q23.1
• Synonyms: CMD1T; LAP2; LEMD4; PRO0868; TP
• Summary: Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]
• Protein Families: Stem cell - Pluripotency, Transmembrane