Annexin VII (ANXA7) (NM_001156) Human Recombinant Protein
CAT#: TP720184
Recombinant protein of human annexin A7 (ANXA7), transcript variant 1
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gln466
|
Tag | tag free |
Predicted MW | 50.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 10mM Tris-HCl, 100mM NaCl, pH 8.0. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001147 |
Locus ID | 310 |
UniProt ID | P20073 |
Cytogenetics | 10q22.2 |
Synonyms | ANX7; SNX; SYNEXIN |
Summary | Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008] |
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Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400464 | ANXA7 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC418291 | ANXA7 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY400464 | Transient overexpression lysate of annexin A7 (ANXA7), transcript variant 1 |
USD 396.00 |
|
LY418291 | Transient overexpression lysate of annexin A7 (ANXA7), transcript variant 2 |
USD 605.00 |
|
PH301226 | ANXA7 MS Standard C13 and N15-labeled recombinant protein (NP_001147) |
USD 2,055.00 |
|
PH321723 | ANXA7 MS Standard C13 and N15-labeled recombinant protein (NP_004025) |
USD 2,055.00 |
|
TP301226 | Recombinant protein of human annexin A7 (ANXA7), transcript variant 1 |
USD 867.00 |
|
TP321723 | Recombinant protein of human annexin A7 (ANXA7), transcript variant 2 |
USD 748.00 |
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