PPIH (NM_006347) Human Recombinant Protein

CAT#: TP720226M

Recombinant protein of human peptidylprolyl isomerase H (cyclophilin H) (PPIH)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Met177
• Tag: N-His
• Predicted MW: 21.4 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_006338
• Locus ID: 10465
• UniProt ID: O43447, Q6FH36
• Cytogenetics: 1p34.2
• Synonyms: CYP-20; CYPH; SnuCyp-20; USA-CYP
• Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]
• Protein Pathways: Spliceosome