NCR3 (NM_001145466) Human Recombinant Protein
CAT#: TP720326M
Recombinant protein of human natural cytotoxicity triggering receptor 3 (NCR3), transcript variant 2
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Leu19-Thr138
|
Tag | C-His |
Predicted MW | 12.8 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_001138938 |
Locus ID | 259197 |
UniProt ID | O14931, Q05D23 |
Cytogenetics | 6p21.33 |
Synonyms | 1C7; CD337; LY117; MALS; NKp30 |
Summary | The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Natural killer cell mediated cytotoxicity |
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