Superoxide Dismutase 1 (SOD1) (NM_000454) Human Recombinant Protein
CAT#: TP720521
Recombinant protein of human superoxide dismutase 1, soluble (SOD1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Gln154
|
Tag | C-His |
Predicted MW | 18.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 20mM Phosphate buffer, 150mM NaCl, pH 7.2. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000445 |
Locus ID | 6647 |
UniProt ID | P00441, V9HWC9 |
Cytogenetics | 21q22.11 |
Synonyms | ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD; STAHP |
Summary | 'The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020]' |
Protein Families | Druggable Genome |
Protein Pathways | Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400160 | SOD1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LY400160 | Transient overexpression lysate of superoxide dismutase 1, soluble (SOD1) |
USD 325.00 |
|
PH300725 | SOD1 MS Standard C13 and N15-labeled recombinant protein (NP_000445) |
USD 2,055.00 |
|
TP300725 | Recombinant protein of human superoxide dismutase 1, soluble (SOD1) |
USD 823.00 |
|
TP750141 | Purified recombinant protein of Human superoxide dismutase 1, soluble (SOD1), full length, with N-terminal His tag, expressed in E. coli, 50ug |
USD 215.00 |
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