IDI2 (NM_033261) Human Recombinant Protein
CAT#: TP720549L
Recombinant protein of human isopentenyl-diphosphate delta isomerase 2 (IDI2)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Val227
|
Tag | N-His |
Predicted MW | 28.9 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 1mM DTT, 0.1mM PMSF, pH 8.0. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_150286 |
Locus ID | 91734 |
UniProt ID | Q9BXS1 |
Cytogenetics | 10p15.3 |
Synonyms | IPPI2 |
Summary | The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016] |
Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
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