ARG2 (NM_001172) Human Recombinant Protein

CAT#: TP720566M

Recombinant protein of human arginase, type II (ARG2), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  His24-Gly330
• Tag: C-His
• Predicted MW: 40.7 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 μm filtered solution of 10mM TrisHCl,10mM NaCl,1mM β-mercaptoethanol,pH7.5.
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001163
• Locus ID: 384
• UniProt ID: P78540, A0A024R6A0
• Cytogenetics: 14q24.1
• Refseq Size: 1981
• Refseq ORF: 1062
• Summary: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways