Nck (NCK1) (NM_006153) Human Recombinant Protein
CAT#: TP720906
Purified recombinant protein of Human NCK adaptor protein 1 (NCK1), transcript variant 1
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Ser377
|
Tag | N-His |
Predicted MW | 45 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Mannitol, pH 8.0. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_006144 |
Locus ID | 4690 |
UniProt ID | P16333, A0A0S2Z4Y3 |
Cytogenetics | 3q22.3 |
Refseq Size | 4421 |
Refseq ORF | 1131 |
Synonyms | NCK; nck-1; NCKalpha |
Summary | The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010] |
Protein Families | Druggable Genome |
Protein Pathways | Axon guidance, ErbB signaling pathway, Pathogenic Escherichia coli infection, T cell receptor signaling pathway |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC416832 | NCK1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC434154 | NCK1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY416832 | Transient overexpression lysate of NCK adaptor protein 1 (NCK1) |
USD 396.00 |
|
LY434154 | Transient overexpression lysate of NCK adaptor protein 1 (NCK1), transcript variant 2 |
USD 396.00 |
|
TP761753 | Purified recombinant protein of Human NCK adaptor protein 1 (NCK1), transcript variant 1, full length, with N-terminal His tag, expressed in E. coli, 50ug |
USD 215.00 |
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