SOAT 2 (SOAT2) (NM_003578) Human Recombinant Protein

CAT#: TP721017

Purified recombinant protein of Human sterol O-acyltransferase 2 (SOAT2)

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Glu397
• Tag: N-Trx&His
• Predicted MW: 42 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 20mM Tris-HCl,100mM NaCl,1mM DTT,10% Glycerol, pH 8.0.
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_003569
• Locus ID: 8435
• UniProt ID: O75908
• Cytogenetics: 12q13.13
• Refseq Size: 2073
• Refseq ORF: 1566
• Synonyms: ACACT2; ACAT2; ARGP2
• Summary: Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
• Protein Families: Transmembrane
• Protein Pathways: Steroid biosynthesis