MIF (NM_002415) Human Recombinant Protein
CAT#: TP721165L
Purified recombinant protein of Human macrophage migration inhibitory factor (glycosylation-inhibiting factor) (MIF)
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Ala115
|
Tag | tag free |
Predicted MW | 12.5 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM PB,150mMNacl,PH7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002406 |
Locus ID | 4282 |
UniProt ID | P14174, I4AY87 |
Cytogenetics | 22q11.23 |
Refseq Size | 561 |
Refseq ORF | 345 |
Synonyms | GIF; GLIF; MMIF |
Summary | This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Phenylalanine metabolism, Tyrosine metabolism |
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