TSLP (NM_033035) Human Recombinant Protein
CAT#: TP723462
Purified recombinant protein of Human thymic stromal lymphopoietin (TSLP), transcript variant 1.
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MYDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ
|
Tag | Tag Free |
Predicted MW | 15 kDa |
Concentration | Resuspend the protein in the desired concentration in proper buffer |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2 |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_149024 |
Locus ID | 85480 |
UniProt ID | Q969D9 |
Cytogenetics | 5q22.1 |
Refseq Size | 2652 |
Refseq ORF | 477 |
Synonyms | thymic stromal lymphopoietin |
Summary | This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
Protein Families | Druggable Genome |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC408574 | TSLP HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC409755 | TSLP HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY408574 | Transient overexpression lysate of thymic stromal lymphopoietin (TSLP), transcript variant 2 |
USD 396.00 |
|
LY409755 | Transient overexpression lysate of thymic stromal lymphopoietin (TSLP), transcript variant 1 |
USD 396.00 |
|
TP723796 | Purified recombinant protein of Human thymic stromal lymphopoietin (TSLP), transcript variant 1 |
USD 265.00 |
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