IL1 Receptor I (IL1R1) (NM_000877) Human Recombinant Protein

CAT#: TP723862

Purified recombinant protein of Human interleukin 1 receptor, type I (IL1R1)

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human IL-1Ra, the region of Asp21-Thr332, from gene Accession# NM_000877
• Tag: Tag Free
• Predicted MW: 38 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 0.2 - 0.6 µg/ml, corresponding to a specific activity of 1.7 - 5.0 x 103 units/mg, determined by the dose dependent inhibition of D10.G4.1 cell proliferation.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_000868
• Locus ID: 3554
• Cytogenetics: 2q11.2-q12.1
• Refseq Size: 4909
• Refseq ORF: 1707
• Synonyms: CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; P80
• Summary: 'This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]'
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway