Inhibin beta A (INHBA) (NM_002192) Human Recombinant Protein

CAT#: TP723875

Purified recombinant protein of Human inhibin, beta A (INHBA)

Specifications

Product Data

• Species: Human
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human Activin A, the region of Gly311-Ser426, from gene Accession# NM13436
• Tag: Tag Free
• Predicted MW: 12.9 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >95%, as determined by Coomassie stained SDS-PAGE
• Buffer: 0.1% TFA, <30% ACN.
• Bioactivity: The ED50 is 1 - 5 ng/ml, corresponding to a specific activity of 0.2 - 1.0 x 106 units/mg, determined by cytotoxic effect on MPC-11 mouse plasmacytoma cells.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_002183
• Locus ID: 3624
• UniProt ID: P08476, A4D1W7
• Cytogenetics: 7p14.1
• Refseq Size: 2175
• Refseq ORF: 1278
• Synonyms: EDF; FRP
• Summary: 'This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016]'
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway