KGF (FGF7) (NM_002009) Human Recombinant Protein

CAT#: TP750010

Recombinant protein of human Fibroblast Growth Factor-7 (KGF) produced in E. coli.


  View other "FGF7" proteins (6)

USD 425.00

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Size
    • 20 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region (Cys32-Thr194) of human FGF7
Tag Tag Free
Predicted MW 19 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4.
Bioactivity Determined by the dose-dependant stimulation of 4MBr-5 cells. ED50 for this effect is typically 0.92-1.38 ng/ml.
Endotoxin < 0.1 EU per 1 µg of the protein by the LAL
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_002000
Locus ID 2252
UniProt ID P21781
Cytogenetics 15q21.2
Refseq Size 3853
Refseq ORF 582
Synonyms HBGF-7; KGF
Summary 'The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]'
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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