MMP3 (NM_002422) Human Recombinant Protein

CAT#: TP750163

Purified recombinant protein of Human matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), Leu246-End, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein MMP3 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Leu246-End) of MMP3
• Tag: N-His
• Predicted MW: 26.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, 150mM NaCl, 10% Glycerine,pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002413
• Locus ID: 4314
• UniProt ID: P08254
• Cytogenetics: 11q22.2
• Refseq Size: 1828
• Refseq ORF: 1431
• Synonyms: CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
• Summary: 'Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Protease