RPGR (NM_000328) Human Recombinant Protein

CAT#: TP750193

Purified recombinant protein of Human retinitis pigmentosa GTPase regulator (RPGR), transcript variant A, full length, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein RPGR was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the full-length of RPGR
• Tag: N-His
• Predicted MW: 90.1 kDa
• Concentration: >50 ug/mL as determined by Bradford protein assay method.
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 250mM NaCl, 10% glycerol
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000319
• Locus ID: 6103
• UniProt ID: Q92834
• Cytogenetics: Xp11.4
• Refseq Size: 3082
• Refseq ORF: 2445
• Synonyms: COD1; CORDX1; CRD; orf15; PCDX; RP3; RP15; XLRP3
• Summary: 'This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008]'
• Protein Families: Druggable Genome