MED6 (NM_005466) Human Recombinant Protein

CAT#: TP760037

Recombinant protein of human mediator complex subunit 6 (MED6), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length MED6
Tag N-His
Predicted MW 28.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_005457
Locus ID 10001
UniProt ID O75586
Cytogenetics 14q24.2
Refseq Size 2386
Refseq ORF 738
Synonyms ARC33; NY-REN-28
Summary Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. [UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome, Transcription Factors

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