TSEN34 (NM_024075) Human Recombinant Protein

CAT#: TP760295

Recombinant protein of human tRNA splicing endonuclease 34 homolog (S. cerevisiae) (TSEN34), transcript variant 1, with N-terminal HIS tag, expressed in E.Coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length TSEN34
Tag N-His
Predicted MW 33.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_076980
Locus ID 79042
UniProt ID Q9BSV6, A0A024R4N9
Cytogenetics 19q13.42
Refseq Size 2294
Refseq ORF 930
Synonyms LENG5; PCH2C; SEN34; SEN34L
Summary This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]

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