MGP (NM_000900) Human Recombinant Protein

CAT#: TP760483

Purified recombinant protein of Human matrix Gla protein (MGP), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


  View other "MGP" proteins (2)

USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length MGP
Tag N-His
Predicted MW 12.2 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000891
Locus ID 4256
UniProt ID P08493, A0A024RAX0
Cytogenetics 12p12.3
Refseq Size 1398
Refseq ORF 309
Synonyms GIG36; MGLAP; NTI
Summary This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016]
Protein Families Secreted Protein

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