BIK (NM_001197) Human Recombinant Protein
CAT#: TP760492
Purified recombinant protein of Human BCL2-interacting killer (apoptosis-inducing) (BIK), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Other products for "BIK"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length BIK
|
Tag | N-His |
Predicted MW | 17.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001188 |
Locus ID | 638 |
UniProt ID | Q13323, A0A024R4X6 |
Cytogenetics | 22q13.2 |
Refseq Size | 966 |
Refseq ORF | 480 |
Synonyms | BIP1; BP4; NBK |
Summary | The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011] |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transmembrane |
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