BIK (NM_001197) Human Recombinant Protein

CAT#: TP760492

Purified recombinant protein of Human BCL2-interacting killer (apoptosis-inducing) (BIK), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug


USD 215.00

In Stock*

Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length BIK
Tag N-His
Predicted MW 17.8 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001188
Locus ID 638
UniProt ID Q13323, A0A024R4X6
Cytogenetics 22q13.2
Refseq Size 966
Refseq ORF 480
Synonyms BIP1; BP4; NBK
Summary The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane

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